|
KMID : 1011820150560100703
|
|
Investigative and Clinical Urology
2015 Volume.56 No. 10 p.703 ~ p.709
|
|
|
Comparison of biochemical recurrence in prostate cancer patients treated with radical prostatectomy or radiotherapy
|
|
Kim Dong-Soo
Jeon Seung-Hyun
Chang Sung-Goo
Lee Sang-Hyub
|
|
|
Abstract
|
|
|
Purpose: We evaluated the biochemical recurrence (BCR) of prostate cancer patients treated by radical prostatectomy (RP) or radiotherapy (RT).
Materials and Methods: Patients who underwent RP or RT as primary definitive treatment from 2007 were enrolled for this study. They were divided into two groups; the low-intermediate risk group and the high risk group according to the National Comprehensive Cancer Network guidelines. We compared differences such as age, prostate specific antigen, Gleason score, follow-up duration, clinical T staging, and BCR. Their BCR-free survival rates were analyzed.
Results: A total of 165 patients were enrolled. There were 115 patients in the low-intermediate risk. Among them, 88 received RP and 27 underwent RT. BCR occurred in 9 of the RP patients (10.2%) and 3 of the RT patients (11.1%). For the high risk group, 50 patients were included. RP was performed in 25 patients and RT in 25 patients. BCR was observed in 4 of the RP patients (16%) and 12 of the RT patients (48%). There were no differences in BCR-free survival for the low-intermediate group (p=0.765). For the high risk group, the RP group had a higher BCR free survival rate (p=0.032).
Conclusions: No difference of BCR and BCR-free survival was seen in the low-intermediate risk group but lower BCR and better BCR-free survival were observed for patients that received RP in the high risk group. RP should be a more strongly considered option when deciding the treatment method for selected high risk patients.
|
|
|
KEYWORD
|
|
|
Prostatic neoplasms, Prostatectomy, Radiotherapy, Recurrence
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
    
|